منابع مشابه
Bone turnover and inhaled corticosteroids.
Bone turnover and inhaled corticosteroids We wish to take issue with several statements made by Kerstjens et al in their recent paper (July 1994;49:652-6). We believe that their conclusion that there is no clear evidence of a detrimental effect of inhaled corticosteroids on bone metabolism is unsubstantiated by the results of their study. They were able to demonstrate a significant fall in oste...
متن کاملInhaled Corticosteroids and Bone Health
Inhaled corticosteroids (ICS) are the cornerstones in the management of bronchial asthma and some cases of chronic obstructive pulmonary disease. Although ICS are claimed to have low side effect profiles, at high doses they can cause systemic adverse effects including bone diseases such as osteopenia, osteoporosis and osteonecrosis. Corticosteroids have detrimental effects on function and survi...
متن کاملInhaled corticosteroids and bone density.
We also previously published our data in an abstract.3 We do not have a good explanation as to why the pneumothorax rate is so variable among different clinical series. We thought that our rate of 35.4% was high but there are reported rates as high as 60%. Patient and lesion selection may be at least as important as technical and operator-related factors. As an example, one clinical series usin...
متن کاملEffect of inhaled corticosteroids on bone.
Inhaled corticosteroids (ICS) are the most effective therapy for asthma currently available. The increasing use of ICS raises the issue of possible adverse systemic effects. Since one of the most important side-effects of oral corticosteroids (OCS) is osteoporosis, this article focuses on current knowledge of the effects of ICS on bone. Generally, doses higher than 1.0 mg/day cause a dose-depen...
متن کاملInhaled Corticosteroids
Inhaled corticosteroids (ICS) are the most effective controllers of asthma. They suppress inflammation mainly by switching off multiple activated inflammatory genes through reversing histone acetylation via the recruitment of histone deacetylase 2 (HDAC2). Through suppression of airway inflammation ICS reduce airway hyperresponsiveness and control asthma symptoms. ICS are now first-line therapy...
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ژورنال
عنوان ژورنال: Thorax
سال: 1995
ISSN: 0040-6376
DOI: 10.1136/thx.50.1.103